Primary hematopoietic cells
- 其他作者: Koller, Manfred R. , Palsson, Bernhard. , Masters, J. R. W.
- 出版: New York : Kluwer Academic Publishers ©2002.
- 稽核項: 1 online resource (342 pages) :illustrations (some color).
- 叢書名: Human cell culture ;volume 4
- 標題: Physiology. , Life SciencesHuman Anatomy & Physiology. , SCIENCE , MEDICAL , Human cell culture. , SCIENCE Life Sciences -- Human Anatomy & Physiology. , MEDICAL Physiology. , Electronic books. , Hematopoietic stem cells. , Blood cells. , Bone marrow cells.
- ISBN: 0306468867 , 9780306468865
- 試查全文@TNUA:
- 附註: Includes bibliographical references. 1. Hematopoietic stem and progenitor cells -- 2. In vitro T-lymphopoiesis -- 3. T-lymphocytes: Mature polyclonal and antigen-specific cell expansion -- 4. The culture, characterization, and triggering of B lymphocytes -- 5. Monocytes and macrophages -- 6. Isolation and cultivation of osteoclasts and osteoclast-like cells -- 7. Isolation and culture of human dendritic cells -- 8. In vitro proliferation and differentiation of CD34+ cells to neutrophils -- 9. Isolation and culture of eosinophils. -- 10. Isolation and culture of mast cells and basophils -- 11. Purification and culture of erythroid progenitor cells -- 12. In vitro development of megakaryocytes and platelets -- 13. Perspectives. ethics, and clinical issues in the use of primary human cells.
- 摘要: This unique comprehensive volume in the Human Cell Culture Series encompasses research methodology for the growth and differentiation of all types of primary hematopoietic cells. Each of the twelve hematopoietic cell types is covered by a leading expert in the field, providing insightful background information along with detailed current culture and assay techniques. In addition to uses for research applications, current and future clinical applications of large-scale culture methods are also discussed. Further, the procurement and processing of primary human tissues is covered in detail. Because of the regulatory and ethical implications associated with use of human and fetal tissues, a separate chapter is included to guide scientists through these issues as well. The generous inclusion of figures and tables, along with a consistent format, makes critical information highly accessible to the reader. Additionally, numerous literature citations provide a valuable reference for students and professionals in the hematology, immunology, oncology and bioengineering fields.
- 電子資源: https://dbs.tnua.edu.tw/login?url=https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=66709
- 系統號: 005297274
- 資料類型: 電子書
- 讀者標籤: 需登入
- 引用網址: 複製連結
The daily production of hundreds of billions of blood cells through the process of hematopoiesis is a remarkable feat of human physiology. Transport of oxygen to tissues, blood clotting, antibody- and cellular-mediated immunity, bone remodeling, and a host of other functions in the body are dependent on a properly functioning hematopoietic system. As a consequence, many pathological conditions are attributable to blood cell abnormalities, and a fair number of these are now clinically treatable as a direct result of hematopoietic research. Proliferation of hematopoietic stem cells, and their differentiation into the many different lineages of functional mature cells, is highly regulated and responsive to many environmental and physiological challenges. Our relatively advanced understanding of this stem cell system provides potentially important insights into the regulation of development in other tissues, many of which are now being acknowledged as stem ce- based, perhaps even into adulthood. The recent public and scientific fanfare following announcement of human embryonic stem cell studies suggests that stem cell research will continue to be a relevant and exciting topic.
來源: Google Book
來源: Google Book
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