附註:Includes bibliographical references and index.
Front Cover; Inside Cover; Table of Contents; Shifts in the Steady State of Actin Assembly are Orchestrated by Capping-Uncapping of Actin Filaments and Promote Changes in; Contributors; Chapter 1 Regulation of Actin Assembly and Disassembly; Chapter 2 The Gelsolin Family of Actin Filament Severers and Cappers; Chapter 3 Molecular Links Between Rho Family GTPases and Myosins; Chapter 4 The Light-Chain-Linked Regulation of Muscle Myosin II; Chapter 5 The Tumor Suppressor l(2)gl: A Myosin-Binding Protein Family; Chapter 6 Focal Adhesion Kinase (FAK) REgulation of Tyr Phosphorylation.
摘要:This monograph is the very first book to comprehensively review the molecular links between G proteins, in particular the Ras/Rho family of GTPases, actin-cytoskeleton and tumorigenesis. More than 25 international experts in this rapidly developing field have contributed up-to-date chapters to this volume. This information will aid in understanding how actin-cytoskeleton is dramatically rearranged during malignant transformation. This information will aid in the design of novel drugs, potentially useful in the treament of cancer.
