附註:Includes bibliographical references and index.
Front Cover -- Inside Cover -- Copyright -- Table of Contents -- Editors / Contributors -- Preface -- Chapter 1: Mechanims of Angiogenesis -- Chapter 2: Angiogenisis and Ischemia -- Chapter 3: The Role of Smooth Muscle Cells and Pericytes in Angiogenesis -- Chapter 4: Integrin v in Health and Disease-Role of v3 in Metastasis, Vascular Remodeling and Angiogenesis -- Chapter 5: PECAM-1 and Angiogenesis -- Chapter 6: Thrombospondin and Angiogenesis -- Chapter 7: The Role of Vascular Endothelial Growth Factor in Angiogenesis -- Chapter 8: Regulation of Angiogenesis by Fibroblast Growth Factors.
Chapter 9: Role of Angiogenesis in Wound Healing -- Chapter 10: Ocular Neovascularization -- Chapter 11: Anti-Angiogenesis Strategies Potential Therapeutic Implications -- Chapter 12: Matrix Metalloproteinase Inhibitors in Angiogenesis-Mediated Disorders with Special Emphasis on Cancer -- Chapter 13: Pharmaceutical Development of an Antiangiogenic Drug-Candidate -- Chapter 14: Surrogate Endpoints as a Measure of Efficacy in Clinical Trials of Angiogenesis Inhibitors -- Chapter 15: Lessons from Clinical Trials of Anti-Angiogenic Drugs in the Treatment of Cancer -- Index -- A -- Angiogenesis.
Angiogenesis inhibitor -- Antiangiogenesis -- Apoptosis -- Atherosclerosis -- avb3 -- avb5 -- Cancer -- Cell adhesion molecules -- CM-101 123, 145 -- Collateral -- Combinatorial chemical libraries -- Cyclic RGD -- Cytokines -- Cytostatic -- Cytotoxic -- D -- Diabetes -- Diabetic retinopathy -- E -- Endothelial cells -- Endothelial migration -- Extracellular matrix -- F -- FGF 87, -- Fibroblast growth factor (FGF) -- G -- Gene therapy -- Growth factor(s) -- H -- Heparan sulfate -- Hyperoxia 68, 111, 112 -- I -- Imaging -- Immunoglobulin -- Inflammation -- Inflammatory diseases -- Integrins.
Ischemia -- M -- Macular degeneration -- Matrix -- Matrix metalloproteinases -- Metastasis -- MMP -- N -- Neuropeptide Y -- O -- Ocular disease -- Oncology -- P -- Pericyte -- Plasminogen -- Proliferation -- Proteases -- R -- Remodeling -- Retina -- Revascularization -- S -- Screening -- Signal transduction -- Smooth muscle cell (SMC) -- Surrogate marker -- T -- Tecogalan 11, 145, 153, 155, 157 -- Therapeutic angiogenesis -- Thrombospondin -- Thymosin -- Tube formation -- Tumor angiogenesis -- Tyrosine kinase -- V -- Vascular remodeling -- VEGF -- VEGF receptors -- W -- Wound angiogenesis.
摘要:The regulation of blood vessel growth underlies many normal biological processes such as reproduction, development, repair and wound healing. It also is a critical feature of pathological processes such as cancer, diabetic retinopathy, macular degeneration, inflammatory arthritis and ischemic heart disease.
