附註:Includes bibliographical references and index.
Glial proinflammatory cytokines mediate exaggerated pain states: implications for clinical pain / Linda R. Watkins, Erin D. Milligan, and Steven F. Maier -- Peripheral hyperalgesic cytokines / Fernando Q. Cunha and Sergio H. Ferreira -- Cytokines and peripheral analgesia / Michael Schfer -- Opioid peptides in immune cells / Eric M. Smith -- Opioid receptors on peripheral sensory neurons / Christoph Stein -- Morphological correlates of immune-mediated peripheral opioid analgesia / Shaaban A. Mousa -- Functional evidence of pain control by the immune system / Halina Machelska -- Opioid receptor expression and intracellular signaling by cells involved in host defense and immunity / Burt M. Sharp -- Experimental evidence for immunomodulatory effects of opioids / Paola Sacerdote, Elena Limiroli and Leda Gaspani -- The immune-suppressive effects of pain / Gayle G. Page -- Invertebrate opiate immune and neural signaling / George B. Stefano [and others] -- Anti-inflammatory effects of opioids / Judith S. Walker.
摘要:This book offers a critical analysis of the concept: the contribution of immune mechanisms in pain and analgesia. It presents a comprehensive overview of this emerging and promising area. The first part constitutes an extensive discussion of diverse sensory effects of cytokines. This book provides evidence for exaggerated pain states produced by cytokins derived from glia within the central nervous system. It also examines the influence of opioids on the immune system.
