Scientific frontiers in developmental toxicology and risk assessment
- 其他作者: National Research Council (U.S.). , National Research Council (U.S.).
- 出版: Washington, DC : National Academy Press ©2000.
- 稽核項: 1 online resource (xviii, 327 pages) :illustrations.
- 標題: Congenital Abnormalities , Risk Assessment. , Abnormalities genetics , Abnormalities, Human Risk factors. , MEDICAL , Developmental Biology. , Humans. , Environmental Exposure adverse effects. , Congenital Abnormalities etiology. , Toxicology. , methods. , Abnormalities etiology , genetics. , genetics , Toxicology methods. , Congenital Abnormalities embryology. , Developmental toxicology. , Electronic book. , adverse effects. , Abnormalities, Human , Abnormalities, Drug-Induced. , Perinatology & Neonatology. , MEDICAL Perinatology & Neonatology. , etiology. , Risk factors. , Electronic books. , Toxicology , Health risk assessment. , Congenital Abnormalities genetics. , etiology , embryology. , Abnormalities , Environmental Exposure
- ISBN: 0309070864 , 9780309070867
- ISBN: 0305070864
- 試查全文@TNUA:
- 附註: Includes bibliographical references (pages 245-277) and index. ""Cover""; ""Front Matter""; ""Preface""; ""Contents""; ""List of Abbreviations""; ""Executive Summary""; ""1 Introduction""; ""2 Developmental Defects and Their Causes""; ""3 Current Practices for Assessing Risk for Developmental Defects and Their Limitations""; ""4 Mechanisms of Developmental Toxicity""; ""5 Human Genetics and the Human Genome Project""; ""6 Recent Advances in Developmental Biology""; ""7 Using Model Animals to Assess and Understand Developmental Toxicity""; ""8 A Multilevel Approach to Improving Risk Assessment for Developmental Toxicity"" ""9 Conclusions and Recommendations""""References""; ""Appendixes""; ""Appendix A Glossary""; ""Appendix B Database Descriptions""; ""Appendix C Signaling Pathways""; ""Appendix D Biographical Information on the Committee on Developmental Toxicology""; ""Index""
- 電子資源: https://dbs.tnua.edu.tw/login?url=https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=56058
- 系統號: 005302345
- 資料類型: 電子書
- 讀者標籤: 需登入
- 引用網址: 複製連結
Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
來源: Google Book
來源: Google Book
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