Fmoc solid phase peptide synthesis :a practical approach
- 其他作者: Chan, Weng C. , White, Peter D.
- 出版: New York : Oxford University Press c 2000.
- 稽核項: 1 online resource (xxiv, 346 pages) :illustrations.
- 叢書名: The practical approach series ;222
- 標題: Festphasentechnik , Synthesis. , Peptidsynthese , ChemistryOrganic. , SCIENCE , SCIENCE Chemistry -- Organic. , Peptides , Solid-phase synthesis. , Electronic books. , Peptídeos (síntese) , Fmoc-Gruppe , Peptides Synthesis.
- ISBN: 019156589X , 9780191565892
- ISBN: 0199637253 , 9780199637256 , 0199637245 , 9780199637249
- 試查全文@TNUA:
- 附註: Includes bibliographical references and index. Basic principles / Peter D. White -- Basic procedures / Weng C. Chan -- Preparation and handling of peptides containing methionine and cysteine / Fernando Albericio -- Difficult peptides / Martin Quibell -- Synthesis of modified peptides / Sarach L. Mellor -- Phosphopeptide synthesis / Peter D. White -- Glycopeptide synthesis / Jan Kihlberg -- Convergent peptide synthesis / Kleomenis Barlos -- Methods of preparing peptide-carrier conjugates / Jan W. Drijfhout -- Chemoselective and orthogonal ligation techniques / James P. Tam -- Purification of large peptides using chemoselective tags / Paolo Mascagni -- Instrumentation for automated solid phase peptide synthesis / Linda E. Cammish -- Manual multiple synthesis methods / B. Dörner.
- 電子資源: https://dbs.tnua.edu.tw/login?url=https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=98445
- 系統號: 005305478
- 資料類型: 電子書
- 讀者標籤: 需登入
- 引用網址: 複製連結
In the years since the publication of Atherton and Sheppard's volume, the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. The basic problems at the time of publication of this earlier work have now for the most part, been solved. As a result, innovators in the field have focussed their efforts to develop methodologies and chemistry for the synthesis of more complex structures. The focus of this new volume is much broader, and covers the essential procedures for the production of linear peptides and more advanced techniques for preparing cyclic, side-chain modified, phospho- and glycopeptides. Many other methods also deserving attention have been included: convergent peptide synthesis; peptide-protein conjugation; chemoselective ligation; and chemoselective purification. The difficult preparation of cysteine and methionine-containing peptides is also covered, as well as methods for overcoming aggregation during peptide chain assembly. Many of the techniques developed for the production of large arrays of peptides by parallel synthesis, such as t-bag, SPOT and PIN synthesis, have naturally been included. Finally, a survey of available automated instrumentation has also been provided.
來源: Google Book
來源: Google Book
評分