附註:Includes bibliographical references.
INTRODUCTION -- Scope of this Report -- Aging and Hormonal Changes -- Testosterone, Human Development, and Health -- Measuring Testosterone Levels -- Testosterone Therapy -- Growing Use of Testosterone Therapy -- Clinical Trials -- TESTOSTERONE AND HEALTH OUTCOMES -- Changes in Endogenous Testosterone Levels with Aging -- Literature Review -- Bone -- Body Composition and Strength -- Physical Function -- Cognitive Function -- Mood and Depression -- Sexual Function -- Health-Related Quality of Life -- Cardiovascular and Hematologic Outcomes -- Prostate Outcomes -- Other Health Outcomes -- Multiple Outcomes -- FUTURE RESEARCH DIRECTIONS -- Strategy for Future Clinical Trials in Older Men -- Recommendations -- Initial Efficacy Trials in Older Men -- Protection of Research Participants: Safety and Ethical Issues -- Additional Areas of Research -- Need for Efficacy Studies in Older Men -- Clinical Studies in Middle-Aged Men.