附註:Includes bibliographical references and index.
1. Thrombosis and cancer : a short history of Trousseau's syndrome / Martin H. Prins and Hans-Martin M.B. Otten -- 2. Pathogenesis of thrombosis in cancer / Anna Falanga, Marina Marchetti, and Alfonso Vignoli -- 3. Platelets and cancer / Abraham Klepfish [and others] -- 4. The role of blood clotting in tumor metastasis : a case for tissue factor / Maria Benedetta Donati and Roberto Lorenzet -- 5. The fibrinolytic system in cancer / Gilles Lugassy and Abraham Klepfish -- 6. Tumor angiogenesis and blood coagulation / Patricia M. Fernandez, Steven R. Patierno, and Frederick R. Rickles -- 7. Risk of cancer in patients presenting with venous thromboembolism / Andrea Piccioli and Paolo Prandoni -- 8. Thrombotic complications of overt cancer / Gilles Lugassy and Boris Yoffe -- 9. Systemic microangiopathies in the cancer patient / Marcel Levi -- 10. Thrombophilia and the risk of venous thromboembolism in cancer / Ron Hoffman and Benjamin Brenner -- 11. Long-term thrombotic complications in cancer-treated patients : the problem of recurrent venous thromboembolism / Graham F. Pineo and Russell D. Hull -- 12. Prevention of cancer-associated thrombosis : an overview / Mark Levine -- 13. Thromboprophylaxis in cancer surgery / Ajay K. Kakkar and Gloria A. Petralia -- 14. Catheter-related arm-vein thrombosis in patients with cancer / Manuel Monreal -- 15. Prevention and treatment of thrombosis in cancer patients / Hans Klaus Breddin and Rupert Bauersachs -- 16. Antimalignant properties of antithrombotic agents / Clara P.W. Klerk, Susanne M. Smorenburg, and Harry R. Bèuller.
摘要:It is now common knowledge that thromboembolic disease is often the earliest manifestation, and one of the most frequent complications, of cancer; and evidence of thromboembolism is seen in up to half of all cancer patients at autopsy. Recent studies have investigated the mechanisms by which cancer causes thrombosis, and emphasized the importance of the coagulation system in angiogenesis and tumor metastasis. It is the purpose of this book to provide comprehensive and timely coverage of our current knowledge of cancer-associated thrombosis, its pathogenesis, clinical features, prevention and therapy. The international contributors to this book, acknowledged specialists in their different disciplines -- hematology, oncology, vascular medicine, pharmacology, internal medicine, and surgery -- have conducted large clinical trials in cancer and thrombosis, and all hematologists, oncologists and physicians involved in the management of cancer patients should find this text of immense value. Book jacket.
