附註:Proceedings of the 10th workshop on advanced methods of PK/PD systems analysis held in, Marina del Rey, California on June 16 and 17, 2003.
Includes bibliographical references and index.
Preliminaries; CONTENTS; Preface; Physiological Modeling of the Small Intestine in Drug Absorption; Intracellular Metabolism of Lamivudine; Mechanism-Based Pharmacodynamic Modeling for Prediction; Mechanism-Based PK/PD Modeling of Digoxin: Role of Receptor Heterogeneity and Postrecepotor Events; Pharmacodynamics and Pharmacogenomics of Corticosteroids: Microarray Studies; Bayesian Inference in Physiologically-Based Pharmacokinetic Modeling: Application to Anticancer Drug Development.
摘要:Advanced Methods of Pharmacokinetic and Pharmocodynamic Systems Analysis Volume 3 is vital to professionals and academicians working in drug development and bioengineering. Both basic and clinical scientists will benefit from this work. This book contains chapters by leading researchers in pharmacokinetic/pharmacodynamic modeling and will be of interest to anyone involved with the application of pharmacokinetic and pharmacodynamics to drug development. The use of mathematical modeling and associated computational methods is central to the study of the absorption, distribution and elimination o.
