Phospholipid metabolism in apoptosis

• 其他作者: Quinn, Peter J. , Kagan, Valerian E.
• 出版: New York : Kluwer Academic/Plenum Publishers 2002.
• 稽核項: 1 online resource (xvi, 340 pages) :illustrations.
• 叢書名: Sub-cellular biochemistry,v. 36
• 標題: SCIENCE Life Sciences -- Cell Biology. , Apoptosis. , Apoptosis Molecular aspects. , Aspect moléculaire. , Apoptosis , SCIENCE , Electronic books. , Apoptose Aspect moléculaire. , Apoptose. , Phospholipids , Lipid membranes. , Apoptose , Molecular aspects. , Membranes lipidiques. , metabolism , Life SciencesCell Biology. , Phospholipids metabolism
• ISBN: 0306467828 , 9780306467820
• ISBN: 0306467828 , 0306-0225 ;
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• 附註: "This volume is a continuation of the journal Sub-cellular biochemistry, volumes 1-4 of which were published quarterly from 1972 to 1975." Includes bibliographical references and index. Machine generated contents note: Lipid Metabolism and Release of Cytochrome c from Mitochondria 1 -- VOLKER LEHMANN and VLADIMIR SHATROV -- Interaction between Cytochrome c and Oxidized Mitochondrial Lipids 19 -- YOSHIHIRO SHIDOJI, SADAAKI KOMURA, NOBUKO OHISHI, -- and KUNIO YAGI -- Plasma Membrane Phospholipid Asymmetry 39 -- PETER J. QUINN -- Apoptosis by Phosphatidylserine in Mammalian Cells 61 -- KAZUO EMOTO and MASATO UMEDA -- Phosphatidylserine Peroxidation during Apoptosis 79 -- Y.Y. TYURINA, V.A. TYURIN, S.X. LIU, C.A. SMITH, -- A.A. SHVEDOVA, N.F. SCHOR and V.E. KAGAN -- Role of Nitric Oxide and Membrane Phospholipid Polyunsaturation in Oxidative Cell Death 97 -- C. PATRICK BURNS, ERIC E. KELLEY, BRETT A. WAGNER, -- and GARRY R. BUETTNER -- Oxidized LDL-induced Apoptosis 123 -- HERVE BENOIST, ROBERT SALVAYRE, and -- ANNE NEGRE-SALVAYRE -- Induction of Apoptosis by Redox-cycling Quinones 151 -- KARIN OLLINGER and KATARINA KAGEDAL -- Apoptosis Induced by Ionizing Radiation 171 -- CRISTIANO FERLINI, RAFFAELE D' AMELIO, -- and GIOVANNI SCAMBIA -- Ceramidases in the Regulation of Ceramide Levels and Function 187 -- SAMER EL BAWAB, CUNGUI MAO, LINA M. OBEID, -- and YASUF A. HANNUN -- Effect of Ceramides on Phospholipid Biosynthesis and Its Implication for Apoptosis 207 -- ARIE B. VAANDRAGER and MARTIN HOUWELING -- Acid Sphingomyelinase-derived Ceramide Signaling in Apoptosis 229 -- ERICH GULBINS and RICHARD KOLESNICK -- Cellular Signaling by Sphingosine and Sphingosine 1-phosphate 245 -- SUSAN PYNE -- Ceramide in Regulation of Apoptosis 269 -- JEAN-PIERRE JAFFREZOU, GUY LAURENT, and THIERRY LEVADE -- Lipid Signaling in CD95-mediated Apoptosis 285 -- ALESSANDRA RUFINI and ROBERTO TESTI -- Phosphatidylinositol 3-kinase, Phosphoinositides and Apoptosis 309 -- GABRIELLA SARMAY -- Index 335.
• 摘要: The last few years have witnessed an explosion of both interest and knowledge about apoptosis, the process by which a cell actively commits suicide. It is now well recognised that apoptosis is essential in many aspects of normal development and is required for maintaining tissue homeostasis. The molecular mechanisms of apoptosis are presently unknown and the subject of focused research effort. It is clear that cell membrane structure and properties play an early part in the induction process. There is increasing evidence that the arrangement of polar lipids in the membrane lipid matrix is an important factor coupled with the homeostatic mechanisms responsible for preserving membrane lipid composition and asymmetry. Changes in membrane permeability are also likely to be involved, possibly as a direct consequence of disturbances in the lipid bilayer matrix. The purpose of this volume is to examine the involvement of membrane lipids in early events of apoptosis. In particular, the role of phospholipids in mitochondrial permeability, membrane lipid asymmetry, and sphingolipid and phospholipid signalling processes in early apoptotic events are reviewed by current researchers in these fields.
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• 系統號: 005308995
• 資料類型: 電子書
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• 引用網址: 複製連結
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