附註:Includes bibliographical references and index.
1. Molecular evolution / Sylvia Nagl -- 2. Gene finding / John G. Sgouros and Richard M. Twyman -- 3. Sequence comparison methods / Christine Orengo -- 4. Amino acid residue conservation / William S.J. Valdar and David T. Jones -- 5. Function prediction from protein sequence / Sylvia B. Nagl -- 6. Protein structure comparison / Ian Sillitoe and Christine Orengo -- 7. Protein structure classifications / Frances Pearl and Christine Orengo -- 8. Comparative modeling / Andrew C.R. Martin -- 9. Protein structure prediction / David T. Jones -- 10. From protein structure to function / Annabel E. Todd --11. From structure-based genome annotation to understanding genes and proteins / Sarah A. Teichmann -- 12. Global approaches for studying protein-protein interactions / Sarah A. Teichmann -- 13. Predicting the structure of protein-biomolecular interactions / Richard M. Jackson -- 14. Experimental use of DNA arrays / Paul Kellam and Xiaohui Liu -- 15. Mining gene expression data / Xiaohui Liu and Paul Kellam -- 16. Proteomics / Malcolm P. Weir, Walter P. Blackstock and Richard M. Twyman -- 17. Data managament [sic] of biological information / Nigel J. Martin -- 18. Internet technologies for bioinformatics / Andrew C.R. Martin -- Glossary -- Index.
摘要:Bioinformatics covers both the more traditional approaches to bioinformatics, including gene and protein sequence analysis and structure prediction, and more recent technologies such as datamining of transcriptomic and proteomic data to provide insights on cellular mechanisms and the causes of disease.
