附註:Includes bibliographical references and index.
1. Assessing Genetic Risk of Cancer / Ronald T. Acton and Lisle M. Nabell -- 2. Genetic Counseling for Inherited Cancer Syndromes / Jill M. Yelland -- 3. Ethical Issues in Genetic Testing for Cancer Susceptibility / Terrence F. Ackerman -- 4. Genes and the Law / Darryl S. Weiman -- 5. Breast Cancer Genetics / Samuel W. Beenken and Kirby I. Bland -- 6. Polyposis Syndromes / C. Neal Ellis, Jr. -- 7. Hereditary Nonpolyposis Colorectal Cancer / Elizabeth G. Grubbs, Roberto J. Manson, and Kirk A. Ludwig -- 8. Hereditary Ovarian Cancer and Other Gynecologic Malignancies / Mack N. Barnes and J. Max Austin -- 9. Genetic Aspects of Urologic Malignancies / Ramsey N. Chichakli and Jeffrey R. Gingrich -- 10. Genetics of Multiple Endocrine Neoplasia / Derrick J. Beech.
摘要:Of the 8 million individuals living with cancer in the United States, up to 800,000 patients have a form of inherited cancer. Inherited cancer syndromes account for 5-10% of all cancers, as evidenced by recent advances in the understanding of such syndromes as Familial Polyposis Syndromes (FAP), Hereditary Nonpolyposis Colon Cancer (HPNCC), and the BRCA1 and 2 breast cancer susceptibility genes. Inherited Cancer Syndromes: Current Clinical Management provides the clinician with a valuable tool for all aspects of patient care in inherited syndromes. Comprehensive, timely chapters present the fundamental principles of genetic counseling and testing, ethical issues, medical-legal issues, and clinical management principles. Chapters on inherited breast cancer, colon cancer, urologic malignancies, gynecologic malignancies, and MEN syndromes provide state-of-the-art information on hereditary risk identification, assessment and management, the role of the genetic counselor, providing optimal patient care, and the important research on the horizon - all written by an expert group of surgical and medical oncologists. Inherited Cancer Syndromes: Current Clinical Management is an important and timely book for surgical oncologists, medical oncologists, radiation oncologists, general surgeons, colorectal surgeons, trainees in surgery and oncology, and genetic counselors.
