附註:Appendixes include abstracts of papers presented at a workshop on "Caffeine formulations for sustainment of mental task performance during military operations," held Feb. 2-3, 1999 in Washington, DC.
Includes bibliographical references (pages 97-112).
Executive summary -- Basic concepts -- Pharmacology of caffeine -- Efficacy of caffeine -- Safety of caffeine usage -- Doses and delivery mechanisms -- Special considerations -- Response to military questions, conclusions, and recommendations.
摘要:This book reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. Also examined are the effects of caffeine on physical performance, cognitive function, and alertness and the alleviation of sleep deprivation impairments. The impacts of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use ofthese supplements. A brief review of some alternatives to caffeine is also provided.