附註:Includes bibliographical references and index.
Introduction: The relevance of genetics to auditory science and clinical audiology -- Genes and mutations in hearing impairment -- Mapping and cloning of genes for inherited hearing impairment -- Population genetics and genetic epidemiology of hearing impairment -- Cytogenetics and gene expression in the cochlea -- Autosomal and X-linked auditory disorders -- Hearing loss and mitochondrial DNA mutations: Clinical implications and biological lessons -- Mouse models for hearing impairment -- Genetic counseling for deafness -- Overview and conclusions.
摘要:Genetics is fundamental to hearing function, and an understanding of genetics enhances both auditory research and the clinical treatment of the hearing impaired. Approaches to the diagnosis and treatment of hearing impairment have developed from technological advances in genetic research. This volume covers gene expression, mutations, mapping and cloning, as well as mitochondrial and cellular genetics. Chapters are also included on the uses of mouse models, genetic epidemiology and genetic counseling specifically for hearing impairment. As a comprehensive review of the genetics of hearing, this book will interest hearing researchers, clinicians and genetic counselors.
