附註:Includes bibliographical references and index.
Book Cover; Title; Contents; List of color plates; List of figures; List of tables; List of contributors; Foreword; Preface; Basic components of gene expression plasmids; Inducible gene expression strategies in gene therapy; Modulation of gene expression by antisense oligonucleotides; Ribozymes as therapeutic agents and genetic tools; Peptide nucleic acids (PNA) binding-mediated target gene transcription; Aptamers for controlling gene expression; Enzymes acting on DNA breaks and its relevance in nucleic acid-based therapy; Compaction and condensation of DNA.
摘要:A comprehensive account of gene therapy from development in the laboratory to clinical applications, with an emphasis on cardiovascular and autoimmune diseases as well as cancer.