New vaccine development :establishing priorities.Volume II,Diseases of importance in Developing Countries

  • 其他作者: Institute of Medicine (U.S.). , National Institute of Allergy and Infectious Diseases (U.S.)
  • 出版: Washington, D.C. : National Academy Press 1986.
  • 稽核項: 1 online resource (1 volume).
  • 標題: ResearchGovernment policy. , Health Risk Assessment. , Developing countries. , Epidemiology. , Health Planning. , MEDICAL Epidemiology. , Vaccination , MEDICAL , Vaccination. , Vaccination United States. , Communicable Disease Control. , Vaccines , Vaccination Developing countries. , Electronic books. , Health Policy. , MEDICAL Health Risk Assessment. , Developing Countries. , United States. , supply & distribution. , Vaccines Research -- Government policy. , Vaccines supply & distribution.
  • ISBN: 030956820X , 9780309568203
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  • 附註: Prepared for the National Institute of Allergy and Infectious Diseases. Includes bibliographical references and indexes. New Vaccine Development Establishing Priorities -- Copyright -- Acknowledgements -- Preface -- Abstract -- Contents -- Summary -- SELECTION OF CANDIDATES -- DETERMINATION OF HEALTH BENEFITS -- Disease Burden Estimates -- Infant Mortality Equivalence Values -- Total Disease Burden Values -- VACCINE CHARACTERISTICS -- Predictions of Vaccine Development -- Definition of Probable Vaccine Target Population -- Treatment of Vaccine Utilization -- Estimation of Time to Licensure, Time to Vaccine Adoption, and Delay of Vaccination Benefits: Discou ... Estimation of Vaccine Preventable IllnessCalculation of Potential Health Benefits for Each Vaccine -- Cost Calculations -- INTERPRETATION OF RESULTS -- FINDINGS, CONCLUSIONS, RECOMMENDATIONS -- REFERENCE -- 2 Priority Setting for Health-Related Investments: A Review of Methods -- METHODS FOR PROJECT RANKING AND SELECTION -- MULTIATTRIBUTE ACCOUNTING -- MULTIATTRIBUTE SCORING -- DECISION ANALYSIS WITH MULTIPLE OBJECTIVES -- COST-EFFECTIVENESS AND COST-UTILITY ANALYSIS -- BENEFIT-COST ANALYSIS -- SELECTION OF AN APPROACH ISSUES IN PROJECT RANKING METHODOLOGIESSources of Estimates -- Sequential or “Lexicographicâ€? Methods -- Interdependence Among Projects -- The “Portfolioâ€? Question -- SUMMARY -- REFERENCES -- 3 Overview of the Analytic Approach -- METHOD -- Calculation Procedures -- INTERPRETATION OF RESULTS -- GUIDELINES -- Step 1 -- Step 2 -- SUMMARY -- REFERENCE -- 4 Comparison of Disease Burdens -- ELEMENTS OF THE SYSTEM FOR COMPARING MORBIDITY AND MORTALITY BURDENS ARISING FROM VARIOUS DISEASES -- Trade-Off Values Expression of Morbidity and Mortality BurdensProcedures Used in Deriving Disease Estimates -- Limitations of the Current Estimates -- VALUE JUDGMENTS IN QUANTIFYING MORBIDITY AND MORTALITY -- IME Perspective Used in This Study -- The Effect of Adopting Other IME Perspectives -- COMPARISON OF COSTS ASSOCIATED WITH DISEASES -- Estimating Aggregate Direct Costs of Diseases in the Developing World -- Estimating Costs for Diseases in Specific Countries or Regions -- Indirect Costs -- FINDINGS -- LIMITATIONS OF THE PROPOSED SYSTEM -- SUMMARY AND CONCLUSIONS RECOMMENDATIONSREFERENCES -- 5 Predictions on Vaccine Development -- THE NEED FOR PREDICTIONS -- SELECTION OF CANDIDATES -- VACCINE CANDIDATES AND TARGET POPULATIONS -- PREDICTIONS ON VACCINE DEVELOPMENT -- Probability of Successful Development -- Cost of Development -- Time to Licensure -- PREDICTIONS ON VACCINE CHARACTERISTICS -- Efficacy -- Adverse Reactions -- Production Technology, Delivery Requirements, and Cost per Dose -- Number of Doses and Route of Administration -- CONCLUSIONS -- REFERENCE
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  • 系統號: 005314675
  • 資料類型: 電子書
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