附註:" ... papers, which were presented at a colloquium entitled "Genetic Engineering of Viruses and of Virus Vectors," organized by Bernard Roizman and Peter Palese (Co-chairs), held June 9-11, 1996, at the National Academy of Sciences in Irvine, Ca"--Page 11287.
"October 1996"--Page 11287.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA -- Contents -- Genetic engineering of viruses and of virus vectors: A preface -- Site-specific integration by adeno-associated virus -- Oncogenic potential of the adenovirus E4orf6 protein -- MATERIALS AND METHODS -- RESULTS -- DISCUSSION -- Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma -- MATERIALS AND METHODS -- RESULTS -- DISCUSSION -- The function of herpes simplex virus genes: A primer for genetic engineering of novel vectors
Genome Structure and Gene ContentThe Role of Selected Viral Genes in Viral Replication -- The Function of Viral Genes in Latency -- Genetic Engineering of Novel Viral Genomes -- Requirements and Design of Viral Vectors -- Conclusions -- The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors -- Direct Virus Therapy -- Conclusion -- Replication-defective herpes simplex virus vectors for gene transfer in vivo
A deletion mutant in the human cytomegalovirus gene encoding IE1491aa is replication defective due to a failure in� MATERIALS AND METHODS -- RESULTS -- DISCUSSION -- Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains -- MATERIALS AND METHODS -- RESULTS -- DISCUSSION -- Epstein-Barr virus vectors for gene delivery to B lymphocytes -- MATERIALS AND METHODS -- RESULTS AND DISCUSSION -- Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety
Applications of pox virus vectors to vaccination: An updateVaccinia-Rabies Glycoprotein G Recombinant -- Fowlpox Virus-Based Recombinants -- Avipox Virus Vectors in Nonavian Species -- Attenuated Vaccinia-Based Vector: NYVAC -- Other Applications of Pox Virus-Based Vectors -- Discussion -- Negative-strand RNA viruses: Genetic engineering and applications -- DNA-Containing Viruses -- Positive-Strand RNA Viruses -- Introduction of cDNA-Derived RNA into a Negative-Strand RNA Virus (Influenza Virus) -- Plasmid-Based Reverse Genetics System for Influenza Virus
Chimeric Influenza Viruses Expressing Foreign Epitopes or PolypeptidesRescue of Infectious Rabies Virus from cDNA -- Rescue of Other Nonsegmented Negative-Strand RNA Viruses -- Perspective -- Foreign glycoproteins expressed from recombinant vesicular stomatitis viruses are incorporated efficiently into virus� -- MATERIALS AND METHODS -- RESULTS -- DISCUSSION -- Specific infection of CD4+ target cells by recombinant rabies virus pseudotypes carrying the HIV-1 envelope spike protein -- MATERIALS AND METHODS -- RESULTS -- DISCUSSION
