附註:Includes bibliographical references (pages 291-468) and index.
1. The context -- 2. Cell senescence -- 3. Cell senescence in aging -- 4. The aging cascade -- 5. Cancer -- 6. Parasitic disease -- 7. The progerias -- 8. The skin -- 9. Cardiovascular system -- 10. Orthopedic systems -- 11. Hematopoetic and immune systems -- 12. Endocrine system -- 13. Nervous system -- 14. Kidneys -- 15. Muscle -- 16. Gastrointestinal system -- 17. The eye -- 18. Towards therapy.
摘要:"Cells, Aging, and Human Disease examines aging from genes to clinical application, analyzing the cellular changes that underlie human age-related disease. The text explores both the fundamental processes of human aging and tissue-by-tissue pathology, as it details current research and state-of-the-art clinical interventions in aging and age-related disease." "Emphasizing human cell mechanisms, the first section of the book presents and analyzes our current knowledge of telomere biology and cell senescence. The text brings the reader up-to-date on telomere maintenance and dynamics. It explains both the limited and general model of cell senescence as the central component in human clinical aging."--Jacket.
