資料來源: Google Book

Bacterial protein toxins :role in the interference with cell growth regulation

  • 其他作者: Lax, Alistair J.,
  • 出版: Cambridge, UK ;New York : Cambridge University Press 2005.
  • 稽核項: 1 online resource (xiv, 239 pages) :illustrations (some color).
  • 叢書名: Advances in molecular and cellular microbiology ;7
  • 標題: Electronic books. , SCIENCE Life Sciences -- Developmental Biology. , SCIENCE , Life SciencesDevelopmental Biology. , Bacterial toxins. , Toxines bactériennes. , Bacterial Toxins , Protéines bactériennes. , Bacterial proteins. , Bacterial Proteins
  • ISBN: 0521177464 , 9780521177467
  • ISBN: 052182091X
  • 試查全文@TNUA:
  • 附註: Includes bibliographical references and index. Toxins and the interaction between bacterium and host / Alistair J. Lax -- The mitogenic Pasteurella multocida toxin and cellular signalling / Gillian D. Pullinger -- Rho-activating toxins and growth regulation / Gudula Schmidt and Klaus Aktories -- Cytolethal distending toxins : a paradigm for bacterial cyclostatins / Bernard Ducommun and Jean De Rycke -- Bartonella signalling and endothelial cell proliferation / Garret Ihler, Anita Verma, and Javier Arevalo -- Type III-delivered toxins that target signalling pathways / Luís J. Mota and Guy R. Cornelis -- Bacterial toxins and bone remodelling / Neil W.A. McGowan [and others] -- Helicobacter pylori mechanisms for inducing epithelial cell proliferation / Michael Naumann and Jean E. Crabtree -- Bacteria and cancer / Christine P.J. Caygill and Michael J. Hill -- What is there still to learn about bacterial toxins? / Alistair J. Lax.
  • 摘要: Bacterial toxins are potent molecular poisons that are released by bacteria to cause disease. This book describes how toxins can enter cells to subvert cell function by interfering with the key processes involved in cell growth and division, and the ability of cells to differentiate into specialised cells.
  • 電子資源: https://dbs.tnua.edu.tw/login?url=https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=129331
  • 系統號: 005316372
  • 資料類型: 電子書
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  • 引用網址: 複製連結
Bacterial toxins that act inside cells interact very specifically with key components of the cell and some even manipulate the cell in subtle ways for their own purposes. These potent toxins, described in this 2005 book, will be of interest to both microbiologists and cell biologists. Some of these toxins are conventional multidomain toxins that are self-programmed to enter cells. Others are delivered by type III mechanisms, often as a package of potent molecules. The molecular targets for all these toxins mediate signal transduction and the cell cycle to regulate the crucial processes of cell growth, cell division and differentiation. Thus these potent toxins are not only responsible for disease, but also provide a powerful set of tools with which to interrogate the biology of the cell. In addition such toxins may act directly to promote carcinogenesis and hence their study is also of interest in a wider context.
來源: Google Book
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