附註:Includes bibliographical references and index.
Cover; Half-title; Title; Copyright; Dedication; Contents; Foreword; Foreword; Contributors; Introduction; SECTION ONE Basic RNAi, siRNA, microRNAs and gene-silencing mechanisms; SECTION TWO Design, synthesis of siRNAs; SECTION THREE Vector development and in vivo, in vitro and in ovo delivery methods; SECTION FOUR Gene silencing in model organisms; SECTION FIVE Drug target validation; SECTION SIX Therapeutic and drug development; SECTION SEVEN High-throughput genome-wide RNAi analysis; Index.
摘要:RNA Interference (RNAi) technology has rapidly become one of the key methods used in functional genomics. In this cutting-edge overview, the basic concepts of RNAi biology are discussed, as well as the current and potential applications, providing an invaluable reference for all those who need to understand this emerging technology.
