附註:Includes bibliographical references and index.
Intro; Contents; Plate Section; List of contributors; List of abbreviations; An introduction to children's cancer and the patient pathway; Section 1 Methods and Clinical Application; 1 Cells, tissues, and the diagnostic laboratory; 2 Methods of genetic analysis applied to pediatric cancer; 3 Blots, dots, amplification, and sequencing; 4 Familial and predisposition syndromes; Section 2 Childhood Cancers; 5 Leukemia; 6 Lymphoma; 7 Tumors of the central nervous system and eye; 8 Neuroblastoma; 9 Primitive neuroectodermal tumours; 10 Rhabdomyosarcoma; 11 Malignant soft tissue tumors of childhood.
12 Pediatric renal neoplasms13 Bone tumors (excluding Ewing's sarcoma); 14 Germ cell tumours; 15 Liver tumors; 16 Carcinoma; Glossary of molecular terms; A; B; C; D; E; F; G; H; I; L; M; N; O; P; R; S; T; W; Y; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; R; S; T; U; V; W; X; Y.
摘要:This is an important and rapidly changing area and the molecular study of paediatric tumours have contributed enormously to our understanding of the pathogenesis of paediatric oncology. The book provides a comprehensive review of molecular pathology and cytogenetic techniques, looking at the recent developments and their impact on our understanding of aetiology, clinical behaviour, diagnosis and management of paediatric cancer.