附註:Includes bibliographical references and index.
Ethics and research with children : an introduction / Eric Kodish -- Evaluating benefits and harms in research on healthy children / Paul B. Miller and Charles Weijer -- Optimizing risks and benefits : the case of rotavirus vaccine / Susan E. Coffin and Robert M. Nelson -- Bioethics meets the barrio : community-based research involving children / Molly Martin and John Lantos -- Adolescent research and parental permission / Lauren K. Collogan and Alan R. Fleischman -- Recruitment of pregnant, minor adolescents and minor adolescents at risk of pregnancy into longitudinal, observational research : the case of the National Children's Study / John Santelli [and others] -- The ethics of newborn screening diabetes research / Lainie Friedman Ross -- Payments for participation of children in research / Douglas S. Diekema -- Justice, lead, and environmental research involving children / Robert M. Nelson -- Behavioral research with children : the fenfluramine challenge / Gerald P. Koocher -- The ethics of predictive genetic testing in prevention trials involving adolescents / Gail Geller -- Research ethics and maternal-fetal surgery / Rebecca Dresser -- Testing drugs in developing countries : pediatric research ethics in an international context / Michelle Eder -- Research and innovation in pediatric surgery : the problem of hypoplastic left-heart syndrome / Erin Flanagan-Klygis and Joel E. Frader -- Near the boundary of research : roles, responsibilities, and resource allocation / Christopher Church [and others] -- Children and placebos / Jessica Wilen Berg -- When eligibility criteria clash with personal treatment choice : a dilemma of clinical research / Benjamin Wilfond and Fabio Candotti -- Involving children with life-shortening illnesses in decisions about participation in clinical research : a proposal for shuttle diplomacy and negotiation / Myra Bluebond-Langner, Amy DeCicco, and Jean Belasco.
摘要:In this edited volume, a diverse group of scholars present and discuss challenging cases in the field of paediatric research ethics. After years of debate and controversy, fundamental questions about the morality of paediatric research persist: is it ever permissible to use a child as a means to an end? How much authority should parents have over decisions about research that involves young children? What should be the role of the older child in decisions about research participation? How do the dynamics of hope and desperation influence decisions about research involving dying children? Should children or their parents be paid for participation in research? What about economic incentives for doctors, researchers and the pharmaceutical industry? Most importantly, how can the twin goals of access to the benefits of clinical research and protection from research risk be reconciled? Following an introductory overview by editor Eric David Kodish, the book is divided into three sections of case studies: Research Involving Healthy Children, Research Involving At Risk Children, and Research Involving Children with Serious Illness.; Each case raises compelling ethical issues, and the analysis presented in each chapter illuminate the challenges posed across a wide spectrum of both research protocols and stories of individual case-based approach, this book provides a balanced and through account of the enduring dilemmas that arise when children become research subjects.
