Sterilisation of tissues using ionising radiations

• 其他作者: Kennedy, John F., , Phillips, Glyn O. , Williams, Peter A.
• 出版: Boca Raton :Cambridge, England : CRC Press ;Woodhead Pub. 2005.
• 稽核項: 1 online resource (v, 341 pages) :illustrations.
• 叢書名: Woodhead Publishing Series in Biomaterials
• 標題: Physiology. , Electronic books. , Life SciencesHuman Anatomy & Physiology. , Tissues Sterilization -- Congresses. , Ionizing radiation Physiological effect. , Effect of radiation on. , Sterilization , SCIENCE , MEDICAL , Tissues , Ionizing radiation Physiological effect -- Congresses. , Physiological effect , MEDICAL Physiology. , Tissues Effect of radiation on. , Ionizing radiation , Physiological effect. , SCIENCE Life Sciences -- Human Anatomy & Physiology. , Conference papers and proceedings. , Effect of radiation on , Tissues Effect of radiation on -- Congresses.
• ISBN: 184569077X , 9781845690779
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• 附註: Proceedings of the 2003 Cellucon Conference, Tissue Sterilization 2003 UK in Wrexham Wales. Includes bibliographical references and index. Cover; STERILISATION OF TISSUES USING IONISING RADIATIONS; Copyright; CONTENTS; THE CELLUCON TRUST; THE CELLUCON TRUST TRUSTEES AND DIRECTORS; THE CELLUCON CONFERENCES; STERILISATION OF TISSUESUSING IONISING RADIATIONS; ACKNOWLEDGEMENTS; EXECUTIVE COMMITTEE; PREFACE; PART 1 STANDARDS FOR TISSUE BANKS AND FOR RADIATION STERILISATION OF TISSUES; IAEA INTERNATIONAL STANDARDS FOR TISSUE BANKS; ABSTRACT; INTRODUCTION; INTRODUCTION; TABLE OF CONTENTS:; Part 1: INTERNATIONAL STANDARDS FOR TISSUE BANKS; SECTION A: General and Organisational Policies; SECTION B: Implementation; ANNEXES. Part 1: GUIDE FOR LEGAL AND REGULATORY CONTROLINTRODUCTION; HISTORICAL PROGRESSION; LAWS AND REGULATIONS; CONCLUSIONS; Part 2: INTERNATIONAL STANDARDS FOR TISSUE BANKS; ANNEXES; REFERENCES; CONTACT ADDRESSES; Part 2: GUIDE FOR LEGAL AND REGULATORY CONTROL; INTRODUCTION; HISTORICAL PROGRESSION; LAWS AND REGULATIONS; CONCLUSIONS; THE DEVELOPMENT OF A CODE OF PRACTICE FOR THE RADIATION STERILISATION OF TISSUE ALLOGRAFTS; ABSTRACT; KEYWORDS; INTRODUCTION; OBJECTIVE AND SCOPE; VALIDATION OF PRE-STERILISATION PROCESSES; VALIDATION OF THE STERILISATION PROCESS. Qualification of the irradiation facilityqualification of the irradiation process; maintenance of validation; routine sterilisation process control; quality, safety and clinical application of the grafts; documentation and certification; management and control; conclusions; bibliography; use of the iaea code of practice for the radiation sterilisation of bone allografts; abstract; keywords; introduction; brief description of the iaea code of practice forthe radiation sterilisation of tissue allografts -- requirements for validation and routine control. Application of the code of practice for radiation sterilisation of bone allografts produced in peruresults; conclusions; acknowledgements; references; part 2 methodology in the sterilisation and preservation of tissues; radiation sources: types and suitability for dose delivery to tissues for sterilisation; abstract; keywords; introduction; radiation sources; radiation quantities and units; radiation detectors; dosimetry at low temperatures; quality control; in-phantom measurements; factors affecting dose homogeneity; biological factors affecting the effect of irradiation; references. Improved method for gamma irradiation of donor tissueabstract; keywords; introduction; background; the challenge; proposed solution; experimentation; biological procedures; calculations; biological results; summary and discussion; references; rapid heat transfer dynamics and cold gamma sterilisation methods for soft tissue allografts; abstract; keywords; introduction; discussion; conclusions; references; comparison of different thawing methods on cryopreserved rabbit aorta; abstract; keywords; introduction; materials & methods; results; discussion; references.
• 摘要: Existing methods and processing for sterilising tissues are proving inadequate in many instances. Infections have been transmitted from the graft to the recipient and in the USA the Centre for Disease Control and other regulatory bodies have drawn attention to the need for a reliable end sterilisation method which does not damage the functionality of the final tissue. Safety of surgical allografts is, therefore, a major concern due to microbial and viral contamination of tissues which is now a problem even in the most sophisticated centres. The Presidents of the main Professional Association of Tissue Banks; American, European and Latin American met in Vienna to review the situation and concluded that the time was opportune to organise an international high level expert meeting, which would identify the best method of using radiation technology to assist in the production of safe tissue allografts Sterilisation of biological tissues with ionising radiations provides the information on this subject presented at an international meeting in Wales, supported by the International Atomic Energy Agency. New methods of protecting the tissues were presented which at the same time allow the use of sufficiently high doses of ionising radiations to inactivate invading organisms. A Code of Practice for the Radiation Sterilisation of Tissues was evaluated and the outcome and the full Code is included in this volume, as well as explorations of all of the methodologies used in the field. Sterilisation of biological tissues with ionising radiations is the only volume of its kind and as such is an invaluable source of information for those working in tissue banks, transplant surgeons and the safety regulators. High-quality papers highlighting the most recent developments in this important areaIncludes the full code of practice for the radiation sterilisation of tissuesEdited by a highly respected team of experts.
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• 系統號: 005319398
• 資料類型: 電子書
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