附註:Includes bibliographical references and index.
Cell cycle activation in neurons: the final exit of brain-morpho-dysregulation / Thomas Arendt -- Paved with good intentions: the link between cell cycle and cell death in the mammalian central nervous system / Yan Yang and Karl Herrup -- The role of presenilins in the cell cycle and apoptosis / Mervyn J. Monteiro -- Cell cycle activation and cell death in the nervous system / Zsuzsanna Nagy -- Cell cycle and chromosome segregation defects in Alzheimer's disease / Huntington Potter -- Alzheimer disease: a new beginning or a final exit? / Mark E. Obrenovich [and others] -- From cell cycle activation to the inhibition of the Wnt pathway: a hypothesis of how neurons die in response to B-Amyloid / Agata Copani [and others].
摘要:Examines the role of cell cycle activation in the molecular mechanisms leading to neuronal degeneration. This work discusses this topic in relation to the major neurological disorders, including Alzheimer's disease, stroke and epilepsy. It provides insights into the molecular determinants of neuronal death.