附註:Includes bibliographical references and index.
Preliminaries; TABLE OF CONTENTS; 1. Molecular Biology of the Plasminogen System; 2. Role of Serine Proteases and Their Inhibitors in Tumor Growth and Angiogenesis; 3. The Gelatinases, MMP-2 and MMP-9-Implications for Invasion and Metastasis; 4. The Collagenases; 5. Stromelysin-3, a Particular Member of the Matrix Metalloproteinase Fmaily; 6. Membrane-type Matrix Metalloproteinases; 7. 3D Structure and Drug Design; 8. Transcriptional Control of Proteases; 9. Tissue Inhibitors of Metalloproteinases in Cancer; 10. Clinical Aspects of Matrix Metalloproteinases.
摘要:This volume offers an update on this aspect of cancer treatment, its interest bias and possible clinical implications, providing an evaluation of the mechanisms of action of proteases and their inhibitors in tumour biology.
