附註:"This study was supported by Grant No. N01-0D-4-2139 between the National Academies and the National Institutes of Health of the U.S. Department of Health and Human Services"--Title page verso.
Includes bibliographical references.
DEFINITION OF PAIN AND DISTRESS AND REPORTING REQUIREMENTS FOR LABORATORY ANIMALS -- Copyright -- Preface -- Contents -- Introduction -- REFERENCE -- Pain and Distress: USDA Perspective -- POLICY 12 -- POLICY 11 -- EXPLANATION OF CATEGORIES -- Column C -- Column D -- Column E -- DISCUSSION -- Pain, Distress, and Reporting Requirements: PHS Policy Perspective -- INTERRELATED ISSUES -- Similarity of Initiatives -- RATS, MICE, AND BIRDS -- HSUS PAIN AND DISTRESS INITIATIVE -- CONCLUSION -- REFERENCE
Assessing Pain and Distress: A Veterinary Behaviorist's PerspectiveASSESSING PAIN AND DISTRESS -- The Dilemma of Definitions -- Issues with Assessing Pain -- Issues with Assessing Distress -- Indicators of Pain -- Indicators of Distress -- Degrees of Stress -- Using Behavior to Assess Pain and Distress -- A Program of Pain and Distress Management -- REFERENCES -- QUESTIONS AND ANSWERS -- Scientific Issues of Pain and Distress -- PAIN VERSUS NOCICEPTION -- Pain -- Nociception -- Noxious Stimuli -- CLASSIFICATIONS OF PAIN -- Protective Pain
Nonprotective PainTISSUE INJURY -- Sensitization -- Hyperalgesia -- STRESS AND DISTRESS -- Definition of Terms -- Reduction with Preemptive Analgesia -- CONCLUSION -- REFERENCES -- QUESTIONS AND ANSWERS -- The Humane Society of the United States Pain and Distress Initiative -- CONTEXT OF THE INITIATIVE -- DEFINITIONS OF TERMS -- ASSESSING DISTRESS -- CONCLUSIONS -- REFERENCES -- QUESTIONS AND ANSWERS -- Pain and Distress Caused by Experimental Procedures� Is It Time for a Reality Check? -- UP-FRONT REPORTING -- Predictability
Planning for Optimal Animal CareCATEGORY D -- PLANNING EXPERIMENTAL METHODS -- SCIENTIFIC JOURNAL REPORTING -- SUMMARY -- REFERENCES -- A View from the Trenches -- WHO I AM -- HOW I GOT HERE -- WHY I CANNOT SUPPORT CHANGES IN THE EXISTING POLICY -- WASTING OUR FISCAL AND HUMAN RESOURCES -- REFERENCE -- QUESTIONS AND ANSWERS -- AALAS Position Paper on the “Recognition and Alleviation of Pain and Distress in Laboratory Animals� -- EVALUATING PAIN AND DISTRESS -- REPORTING ANIMAL USE -- ALLEVIATING PAIN AND DISTRESS -- TRAINING OF PERSONNEL
ROLES OF THE VETERINARIAN, IACUC, AND INVESTIGATORREFINEMENT -- CONCLUSION -- QUESTIONS AND ANSWERS -- On Regulating Pain and Distress -- BENEFIT THE ANIMALS -- KEEP IT SIMPLE -- ETHICAL ISSUES -- QUESTIONS AND ANSWERS -- An Industrial Perspective -- SOURCES OF PAIN -- ASSESSMENT -- SHARED RESPONSIBILITY -- Institutions -- Investigators -- IACUC -- Veterinarians -- PAIN AND DISTRESS INITIATIVES -- HSUS -- USDA -- REPORTING -- Categorization -- CONCLUSION -- REFERENCES -- QUESTIONS AND ANSWERS -- Corners Still Unswept -- INTRODUCTIONS
