附註:Towards a better understanding of a familiar disease.
Inflammatory Bowel Diseases 2003 -- From Genetics to Biological Therapy -- Genetics of Inflammatory Bowel Diseases -- Past, Present, and Future -- Environmental Influences on Inflammatory Bowel Disease Manifestations -- Rationale for Probiotic and Antibiotic Treatment Strategies in Inflammatory Bowel Diseases -- New Diagnostic Avenues in Inflammatory Bowel Diseases -- Osteoporosis and Other Extraintestinal Symptoms and Complications of Inflammatory Bowel Diseases -- Standard Therapy of Crohn's Disease -- Standard Treatment of Ulcerative Colitis.
Surgery for Inflammatory Bowel Diseases -- Biological Therapy in IBD.
摘要:Although chronic inflammatory bowel diseases (IBD) have been described for more than a century and despite the progress made in the last decade, their etiology and pathogenesis are still not completely understood. This publication presents the state-of-the-art regarding etiology, pathogenesis, diagnosis, clinical presentation and treatment of IBD. Starting with a description of the most recent developments regarding the genetic basis of IBD, the attention is then turned to environmental factors such as diet, smoking, infectious agents and, most currently, hygiene. This is followed by a description of the possibilities and limitations of various recent imaging methods such as CT, MRI and capsule endoscopy. The discussion then moves on to extraintestinal symptoms and complications of IBD, including osteoporosis as well as some other complications, followed by an account of various treatment options including a review of standard treatments for IBD, surgical therapy and lastly 'biological therapies'. Written for both clinicians and researchers, this publication summarizes recent progress and will help to prepare the way for further research into the genotypes and their treatment.
