Handbook on nanobiomaterials for therapeutics and diagnostic applications[electronic resource]

• 其他作者: Anand, Krishnan,
• 出版: San Diego : Elsevier 2021.
• 稽核項: 1 online resource (612 p.).
• 標題: Nanostructured materials. , Biomedical materials. , Nanobiotechnology. , Electronic books.
• ISBN: 0128210133 , 9780128210130
• 試查全文@TNUA:
  
• 附註: Includes index. Intro -- Handbook on Nanobiomaterials For Therapeutics and Diagnostic Applications -- Copyright -- Contents -- Contributors -- Chapter 1 Nanosomes for drug delivery -- 1.1 Introduction -- 1.2 Drug delivery system -- 1.3 Pharmacokinetics and pharmacodynamics -- 1.4 Types of nanosomes in drug delivery -- 1.4.1 Endosomes in drug delivery -- 1.4.2 Exosomes in drug delivery -- 1.4.3 Liposomes in drug delivery -- 1.4.4 siRNA-encapsulated nanosomes in drug delivery -- 1.4.4.1 Epidemiology -- 1.5 Nanosomes and gene therapy -- 1.6 Nanosome transportation mechanisms. 1.7 Blockades of nanosome trafficking -- 1.8 Drug release -- 1.9 Conclusion -- References -- Chapter 2 Nanomaterials for bioimaging studies -- 2.1 Introduction -- 2.2 Dye-loaded fluorescent silica nanoparticles (SiNPs) in bioimaging -- 2.2.1 Properties of SiNPs -- 2.2.2 Synthesis of SiNPs -- 2.2.3 Bioimaging -- 2.2.3.1 Typical fluorescent dye-doped SiNPs -- 2.2.3.2 Near-infrared fluorescent dye-doped SiNPs -- 2.2.3.3 Two-photon fluorescent dye silica nanoparticles -- 2.3 Imaging, targeting, and drug delivery using multifunctional inorganic nanoparticles (MiNPs). 2.4 Lanthanide-doped upconverting nanoparticles -- 2.4.1 The fundamental mechanism of UCNPs -- 2.4.2 Synthesis of UCNPs -- 2.4.3 UCNPs as image contrasting agents -- 2.5 Conclusions -- References -- Chapter 3 Exosome RNAs as biomarkers for cancer therapy -- 3.1 Introduction -- 3.2 Exosomes in cancer -- 3.3 Exosomes from body fluids -- 3.3.1 Resistance to cancer therapeutics -- 3.3.2 Nanodiagnostic exosomes by electrochemical biosensing -- 3.3.3 Characterization of salivary exosomes -- 3.4 Exosomes derived from tumor cells -- 3.4.1 Role of exosomes in metastasis of cancer cells. 3.4.2 State of exosomes within the enlargement of cancer tissue amidst angiogenesis -- 3.5 Exosomes-Role in maintaining a strategic distance from an assault from immune cells -- 3.6 Potential benefits of exosomal RNAs in malignant growth diagnostics and treatment -- 3.6.1 Exosomal ncRNAs as malignancy indicative biomarkers -- 3.6.2 Uses of exosomal noncoding RNAs (ncRNAs) as cancer therapeutics -- 3.7 Conclusion -- References -- Chapter 4 Tumoral delivery of nanotherapeutics -- 4.1 Introduction -- 4.2 Therapeutics employed for tumor treatment -- 4.2.1 Chemotherapy -- 4.2.2 Genetic material. 4.2.3 Photodynamic therapy (PDT) -- 4.2.4 Photothermal therapy (PTT) -- 4.2.5 Immunotherapy -- 4.2.6 Sonodynamic therapy -- 4.3 Barriers to tumoral delivery of nanotherapeutics -- 4.3.1 Barriers in the systemic circulation -- 4.3.2 Barriers in the tumor microenvironment -- 4.3.3 Barriers at cellular level -- 4.3.4 Heterogeneity in vascular density among different tumors -- 4.4 Potential of nanocarriers for tumoral delivery of therapeutics -- 4.4.1 Chemotherapy -- 4.4.2 Gene therapy -- 4.4.3 PDT -- 4.4.4 PTT -- 4.4.5 Combination therapy -- 4.4.6 Targeted therapy -- 4.4.6.1 Passive targeting. 4.4.6.2 Active targeting.
• 電子資源: https://dbs.tnua.edu.tw/login?url=https://www.sciencedirect.com/science/book/9780128210130
• 系統號: 005324276
• 資料類型: 電子書
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• 引用網址: 複製連結
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